Biological network analysis with CentiScaPe: centralities and experimental dataset integration

Biological network analysis with CentiScaPe: centralities and experimental dataset integration

The growing dimension and complexity of the available experimental data generating biological networks have increased the need for tools that help in categorizing nodes by their topological relevance. Here we present CentiScaPe, a Cytoscape app specifically designed to calculate centrality indexes used for the identification of the most important nodes in a network. CentiScaPe is a comprehensiv...

Biological network analysis with CentiScaPe: centralities

The growing dimension and complexity of the available experimental data generating biological networks have increased the need for tools that help in categorizing nodes by their topological relevance. Here we present CentiScaPe, a Cytoscape app specifically designed to calculate centrality indexes used for the identification of the most important nodes in a network. CentiScaPe is a comprehensiv...

Analyzing biological network parameters with CentiScaPe

SUMMARY The increasing availability of large network datasets along with the progresses in experimental high-throughput technologies have prompted the need for tools allowing easy integration of experimental data with data derived form network computational analysis. In order to enrich experimental data with network topological parameters, we have developed the Cytoscape plug-in CentiScaPe. The...

Visual analysis of network centralities

Centrality analysis determines the importance of vertices in a network based on their connectivity within the network structure. It is a widely used technique to analyse network-structured data. A particularly important task is the comparison of different centrality measures within one network. We present three methods for the exploration and comparison of centrality measures within a network: ...

CentiBiN Centralities in Biological Networks